Reading this could save your dog’s life.
Medium-chain acyl-CoA dehydrogenase deficiency (MCADD), a fatty acid oxidation disorder, is an inherited disease affecting the Cavalier King Charles Spaniel breed.
This condition prevents the normal use of fat as an alternative energy source during fasting or increased metabolic demands.
Affected animals cannot burn fat for energy when their bodies run out of glucose, and as a result, they may be affected by low blood sugar, altered central nervous system function, coma, or sudden death. With an early diagnosis, MCADD can be managed successfully by diet.
Owners are being advised not to feed MCT oils unless their dog has been tested clear for the ACADM mutation causing the MCAD deficiency.
While it is a well-documented condition in humans, there’s less extensive literature and research about MCADD in dogs.
Nonetheless, here’s some basic information on what you might expect if a dog has a metabolic disorder. This is new to us, so there may be further clinical signs found as more cases are diagnosed.
If you suspect a pet has a metabolic disorder like MCADD or is showing unusual clinical signs such as frequent lethargy, hypoglycemia, or muscle weakness, it is crucial to consult with a veterinarian. This is a newly found condition, so many vets may not be fully aware of it, although, with some research, they should be able to give you more information.
If your Cavalier has ever had a seizure or lethargy with an unknown cause, even if it’s just a one-off, you should get the MCADD DNA test. It is inexpensive and could save your dogs life. Available at www.laboklin.co.uk and https://www.cagt.co.uk
There is a fantastic Facebook group for further information – MCADD in the Cavalier King Charles Spaniel